Sarkar, Satavisha; Banerjee, Arghya; Yao, Wang; Patterson, Eric V.; Ngai, Ming-Yu published the artcile< Photocatalytic Radical Aroylation of Unactivated Alkenes: Pathway to β-Functionalized 1,4-, 1,6-, and 1,7-Diketones>, Related Products of 1003-21-0, the main research area is unsym diketone preparation photoredox catalysis; aroyl chloride unactivated alkene aroylation photochem; 1,n-diketones; aroylation; migration; photoredox catalysis; unactivated alkenes.
The development of a photocatalytic strategy for the synthesis of β-functionalized unsym. 1,4-, 1,6-, and 1,7-diketones from aroyl chlorides and unactivated alkenes at room temperature is reported. The mild reaction conditions not only tolerate a wide range of functional groups and structural moieties, but also enable migration of a variety of distal groups including (hetero)arenes, nitrile, aldehyde, oxime derivative, and alkene. The efficiency of chirality transfer, factors that control the distal-group migration, and synthesis of carbocycles and heterocycles from the diketones are also described. Mechanistic studies suggest a reaction pathway involving a photocatalytic radical aroylation of unactivated alkenes followed by a distal-group migration, oxidation, and deprotonation to afford the desired diketones.
ACS Catalysis published new progress about Alcohols, unsaturated Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (tertiary). 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, Related Products of 1003-21-0.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem