Chen, Shuai; Graceffa, Russell F.; Boezio, Alessandro A. published the artcile< Direct, Regioselective N-Alkylation of 1,3-Azoles>, COA of Formula: C4H5BrN2, the main research area is regioselective alkylation azole purine organomagnesium reagent.
Regioselective N-alkylation of 1,3-azoles is a valuable transformation. Organomagnesium reagents were discovered to be competent bases to affect regioselective alkylation of various 1,3-azoles. Counterintuitively, substitution selectively occurred at the more sterically hindered nitrogen atom. Numerous examples are provided, on varying 1,3-azole scaffolds, with yields ranging from 25 to 95%.
Organic Letters published new progress about Alkylation, regioselective. 1003-21-0 belongs to class imidazoles-derivatives, and the molecular formula is C4H5BrN2, COA of Formula: C4H5BrN2.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem