Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 693-98-1, name is 2-Methyl-1H-imidazole, A new synthetic method of this compound is introduced below., SDS of cas: 693-98-1
2-methyl-imidazole is reacted with a molar equivalent of acrylonitrile in a mixture of triethylamine and toluene. The mixture is heated at 50 C. to generate an intermediate imidazole compound linked to acrylonitrile, N-propanenitrile-2-methyl-imidazole. The nitrile bond is reduced by bubbling hydrogen gas into a solution of N-propanenitrile-2-methyl-imidazole in methanol catalyzed by Rainey Nickel. N-propylamine-2-imidazole is generated from the reduction reaction as seen in Scheme I.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA; Bara, Jason Edward; (17 pag.)US2018/21723; (2018); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem