The author of 《A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues》 were Ren, Mingguang; Xu, Qingyu; Wang, Shoujuan; Liu, Lu; Kong, Fangong. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2020. Recommanded Product: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid The author mentioned the following in the article:
A cancer cell targeted fluorescent viscosity probe has been designed and synthesized to specifically visualise viscosity changes in biotin receptor (BiR) pos. cells over biotin neg. cells via dual-mode fluorescence imaging: fluorescence intensity mode and fluorescence lifetime mode. In the experiment, the researchers used 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5Recommanded Product: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid)
5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid(cas: 58-85-5) may be used to elute proteins from avidin/streptavidin resins. It has been used for culturing of oligodendrocytes.Recommanded Product: 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid The biotin/avidin or biotin/streptavidin interaction is utilized in many labeling and purification schemes.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem