The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. Safety of 1H-Imidazole-2-carbaldehyde.
Joel, C.;Jim Livingston, D.;Biju Bennie, R.;Jeyanthi, D.;Vijay Solomon, Rajadurai research published 《 Designing bifunctional phenanthroimidazole chromophores for highly selective ratiometric chemosensing of Cu2+/F– and Co2+/F– ions in organic solvents》, the research content is summarized as follows. Two new phenanthroimidazole based highly sensitive and selective bifunctional probes 2-(1H-imidazol-2-yl)-1H-phenanthro[9,10-d]imidazole (PQIM) and 2-(1H-indol-3-yl)-1H-phenanthro[9,10-d]imidazole (PQIN) have been synthesized which could act as ratiometric sensors. Upon addition of analytes, the receptors exhibited pronounced fluoroionophoric behavior on account of internal charge transfer mechanism (ICT). The mol. sensing studies of both the ligands were explored using UV-visible and fluorescence spectroscopic techniques. It has been observed that the receptor PQIM shows better recognition behavior towards Cu2+/F- while the ligand PQIN exhibited enhanced sensing activity towards Co2+/F-. The binding stoichiometry of the receptor and cation/anion complex was probed to be 1:1 from Job’s plot which were further confirmed from ESI mass spectral techniques and 1H NMR titrations Further, the binding interactions between these ions (Co2+, Cu2+ and F–) with their resp. receptors are probed by d. functional theory calculations This study extends our knowledge on designing chem. compounds that could act as chemosensors in selective binding of certain anions/cations and their sensing mechanisms.
Safety of 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem