Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemical Communications (Cambridge, United Kingdom) called Highly active bidentate N-heterocyclic carbene/ruthenium complexes performing dehydrogenative coupling of alcohols and hydroxides in open air, Author is Wang, Zhi-Qin; Tang, Xiao-Sheng; Yang, Zhao-Qi; Yu, Bao-Yi; Wang, Hua-Jing; Sang, Wei; Yuan, Ye; Chen, Cheng; Verpoort, Francis, which mentions a compound: 3724-19-4, SMILESS is OC(=O)CCC1=CC=CN=C1, Molecular C8H9NO2, Product Details of 3724-19-4.
Eight bidentate NHC/Ru complexes were designed and prepared In particular, compound I displayed extraordinary performance even in open air for the dehydrogenative coupling of alcs. and hydroxides. Notably, an unprecedentedly low catalyst loading of 250 ppm and the highest TON of 32 800 and TOF of 3200 until now were obtained.
Different reactions of this compound(3-Pyridinepropionic acid)Product Details of 3724-19-4 require different conditions, so the reaction conditions are very important.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem