Name: Methyl 5-chlorofuran-2-carboxylate. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Methyl 5-chlorofuran-2-carboxylate, is researched, Molecular C6H5ClO3, CAS is 58235-81-7, about QSAR in a series of muscarinic agents. Note II. Pyridine and furan derivatives. Author is Pratesi, P.; Villa, L.; Ferri, V.; De Micheli, C.; Grana, E.; Santagostino Barbone, M. G.; Grieco, C.; Silipo, C.; Vittoria, A..
Substituted furfuryl- and picolyltrimethylammonium salts, some of which were synthesized, were evaluated for ligand-muscarinic receptor interaction on isolated rat jejunum. The affinity of the ligand, expressed as pD2 values, was dependent on hydrophobic and steric parameters of the ring substituent. QSARs between muscarinic receptor and ligand are discussed.
Different reactions of this compound(Methyl 5-chlorofuran-2-carboxylate)Name: Methyl 5-chlorofuran-2-carboxylate require different conditions, so the reaction conditions are very important.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem