Tie, Leopold; Raileanu, Mina; Bacalum, Mihaela; Codita, Irina; Negrea, Stefania Madalina; Caracoti, Costin Stefan; Dragulescu, Elena-Carmina; Campu, Andreea; Astilean, Simion; Focsan, Monica published the article 《Versatile polypeptide-functionalized plasmonic paper as synergistic biocompatible and antimicrobial nanoplatform》. Keywords: polypeptide plasmonic paper synergistic biocompatible antimicrobial nanoplatform; Escherichia coli; Staphylococcus aureus; antimicrobial activity; antimicrobial peptides; biocompatibility; gold nanospheres; paper platform.They researched the compound: Hydrogen tetrachloroaurate(III) trihydrate( cas:16961-25-4 ).Reference of Hydrogen tetrachloroaurate(III) trihydrate. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:16961-25-4) here.
Nowadays, thanks to nanotechnol. progress, which itself guides us more and more closely toward not only the efficient design of innovative nanomaterials or nanostructures, but to the improvement of their functionality, we benefit from an important asset in the battle against pathogenic illnesses. Herein, we report a versatile biocompatible plasmonic nanoplatform based on a Whatman paper incorporating pos.-charged gold nanospherical particles via the immersion approach. The morphol. characterization of the as-engineered-plasmonic paper was examined by SEM (SEM) and HRTEM (high-resolution transmission electron microscopy) investigations, while its surface chem. modification with a synthetic polypeptide, specifically RRWHRWWRR-NH2 (P2), was proved by monitoring the plasmonic response of loaded gold nanospheres and the emission signal of P2 via fluorescence spectroscopy. The as-functionalized plasmonic paper is non-cytotoxic towards BJ fibroblast human cells at bactericidal concentrations Finally, the antimicrobial activity of the P2-functionalized plasmonic paper on both planktonic bacteria and biofilms was tested against two reference strains: Gram-pos. Bacteria, i.e., Staphylococcus aureus and the Gram-neg. Bacteria, i.e., Escherichia coli, determining microbial inhibition of up to 100% for planktonic bacteria. In line with the above presented nanoplatform proper design, followed by their functionalization with active antimicrobial peptides, new roads can be open for determining antibiotic-free treatments against different relevant pathogens.
After consulting a lot of data, we found that this compound(16961-25-4)Reference of Hydrogen tetrachloroaurate(III) trihydrate can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem