Prakash, J.; Prema, D.; Venkataprasanna, K. S.; Balagangadharan, K.; Selvamurugan, N.; Venkatasubbu, G. Devanand published the article 《Nanocomposite chitosan film containing graphene oxide/hydroxyapatite/gold for bone tissue engineering》. Keywords: chitosan graphene oxide hydroxyapatite gold nanocomposite bone tissue engineering; Alkaline phosphatase; Antibacterial activity; Biocompatibility; Chitosan; Graphene oxide; Hydroxyapatite.They researched the compound: Hydrogen tetrachloroaurate(III) trihydrate( cas:16961-25-4 ).HPLC of Formula: 16961-25-4. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:16961-25-4) here.
Recently, polymer based biomaterials are utilized in medical fields including surgical sutures, drug delivery devices, tissue supports and implants for interior bone fixation. However, polymer based implants leads to the formation of bio-films that are highly susceptible to microbial adhesion. In this study, we have fabricated Chitosan/Polyvinyl alc./Graphene oxide/Hydroxyapatite/gold films for potential orthopedic application. Graphene oxide/Hydroxyapatite/gold nanocomposite (GO/HAP/Au) was synthesized by simple hydrothermal method and GO/HAP/Au nanocomposite incorporated polymeric film was fabricated using gel casting method. The morphol., phase composition, crystalline structure and chem. state of the nanocomposite were characterized using as XRD, HR-TEM, FE-SEM and FT-IR. The bio-films were found to be biocompatible with mouse mesenchymal cells and it enhanced osteoblast differentiation as evidenced by more alk. phosphatase activity at the cellular level. Hence, these results suggested that the developed nanocomposites films are osteogenic potential for treating bone and bone-related diseases. Antibacterial anal. of the films shows high inhibition zones against Gram pos. and Gram Neg. bacteria (Escherichia coli, streptococcus mutans, Staphylococcus aureus and Pseudomonas aeruginosa). Thus, the obtained nanocomposites bio-films are highly biocompatible and it can be used for bone regeneration application.
There is still a lot of research devoted to this compound(SMILES：Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+])HPLC of Formula: 16961-25-4, and with the development of science, more effects of this compound(16961-25-4) can be discovered.
Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem