New explortion of 58235-81-7

Here is a brief introduction to this compound(58235-81-7)HPLC of Formula: 58235-81-7, if you want to know about other compounds related to this compound(58235-81-7), you can read my other articles.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Studies of furan derivatives. I. Synthesis of chlorofuran derivatives, published in 1958, which mentions a compound: 58235-81-7, Name is Methyl 5-chlorofuran-2-carboxylate, Molecular C6H5ClO3, HPLC of Formula: 58235-81-7.

Tetrachloro-2-furoic acid (I) dissolved in methanol, dropped into methanolic NaOH solution, previously chilled below 0°, with stirring, the mixture kept 24 hrs., and methanol removed under reduced pressure, gave 3,4-dichloro-2-furoic acid (II), m. 167-8° (dilute EtOH). II (8 g.) heated in 50 cc. water at 100°, 20 g. 1% Na-Hg added gradually, and the mixture kept at 100° for 1 hr. with stirring, cooled, and acidified deposited 3.8 g. 3-chloro-2-furoic acid (III), m. 148-9° (water). III yielded a chloride (IV) with SOCl2. IV added 1 mole Cl; the mixture was distilled at room pressure, the fraction b. 180-20° gradually added to a cold ethanolic solution of NaOH with stirring, the deposit filtered off, and dissolved in water, and the solution acidified with HCl to give 5-chloro-2-furoic acid (V), yield 4%, m. 176-7° (dilute MeOH). A similar run with Me 5-chloro-2-furoate (VI), which was prepared from 30 g. V, 60 cc. ethanol, and 15 g. concentrated H2SO4, gave 3,5-dichloro-2-furancarboxylic acid (VII) in 22% yield, m. 155-6° (dilute methanol). The acid chloride of II (8 g.), heated with 0.8 g. Pd-BaSO4 (5%) and 75 cc. dry xylene in 140-5° oil bath while passing H with stirring, gave 3,4-dichlorofurfural in 83% yield, m. 52-3°. A similar run with the chlorides of III, VI, and VII gave 3-chlorofurfural (VIII), 60%, m. 28°, 5-chlorofurfural, 7%, m. 31-3%, and 3,5-chlorofurfural, 59%, m. 11-13°, b4 59-61°, resp.

Here is a brief introduction to this compound(58235-81-7)HPLC of Formula: 58235-81-7, if you want to know about other compounds related to this compound(58235-81-7), you can read my other articles.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem