In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6775-40-2 as follows. category: imidazoles-derivatives
2-amino-4-phenyl-1H-imidazole and 1-iodopropane are dissolved in absolute ethanol,Reaction at 80 and catalytic system for 20h, cooling to 50 ,1-propyl-4-phenyl-1H-imidazol-2-amine is prepared, in which the catalytic system consists of cuprous iodide,8-hydroxyquinoline and K3PO4,The molar ratio of 2-amino-4-phenyl-1H-imidazole to 1-iodopropane is 1: 1.5.The molar ratio of cuprous iodide to 8-hydroxyquinoline is 1: 1.7.The molar ratio of cuprous iodide to 2-amino-4-phenyl-1H-imidazole is 0.15: 1,The molar ratio of K3PO4 to 2-amino-4-phenyl-1H-imidazole is 2.4: 1;
According to the analysis of related databases, 6775-40-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Donghua University; Cai Zhengguo; Li Yanqing; Xiao Ru; (35 pag.)CN110396116; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem