Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4887-80-3, name is 5-Methoxy-1H-benzo[d]imidazole, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C8H8N2O
5-methoxybenzimidazole (0.296 g, 2 mmol), 2-(4-Diethylamino-2-hydroxy) benzoylbenzoic acid (0.626 g, 2 mmol) were mixed and addedinto concentrated H2SO4 (3 mL), heated at 100 C for 6 h, and thenslowly cooling to ambient temperature. The resulting mixture wasslowly poured into ice cold water, neutralized by saturated aqueousNaHCO3 followed by extraction with CH2Cl2 (50 mL×3). The organiclayers were collected and dried over Na2SO4, which was subsequentlyevaporated to remove CH2Cl2. Finally, target compound BiF was obtainedas a white powder in yield of 82.0% (0.768 g) through columnchromatography over silica gel eluting with CH2Cl2/CH3OH (v/v=20 :1). M.p.>300 C. ESI-HRMS: calcd. m/z 412.1661 for [M + H]+,found m/z 412.1615 for [M + H]+; 1H NMR (400 MHz, DMSO-d6) delta(ppm) 8.04 (dd, J=6.0 Hz, 2.2 Hz, 1H), 7.65-7.54 (m, 4H), 7.19 (d,J=8.8 Hz, 2H), 6.61 (d, J=8.8 Hz, 1H), 6.48 (d, J=2.4 Hz, 1H), 6.39(dd, J=8.8 Hz, 2.4 Hz, 1H), 3.67 (q, J=7.0 Hz, 4H), 1.18 (t,J=7.0 Hz, 6H). 13 C NMR (100 MHz, DMSO-d6) delta (ppm) 170.36,152.58, 149.65, 140.71, 135.12, 129.84, 128.52, 127.11, 125.28,124.10, 113.10, 108.68, 104.80, 97.57, 84.05, 44.61, 12.65.
According to the analysis of related databases, 4887-80-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Huang, Kun; Han, Defang; Li, Xianglin; Peng, Mengni; Zeng, Xianshun; Jing, Linhai; Qin, Dabin; Dyes and Pigments; vol. 171; (2019);,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem