Electric Literature of 45676-04-8, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 45676-04-8 as follows.
To a 250 mL three-necked flask, 6.8 g of N-tert-butylimidazole and 9.3 g (molar ratio 1: 1) of chloroform were added to a reactor equipped with a magnetic stirrer, a heating apparatus and a condensing apparatus, and toluene was added as a solvent , 2.5 g of sodium hydride as the catalyst, at 90 C, stirring reaction 12h, separation and purification of N-tert-butyl imidazole. 6.2 g of the above product and 6.2 g (molar ratio 1: 1) of chloromethyltrimethylsilane were added to a reaction vessel equipped with a magnetic stirrer, a heating apparatus and a condensing apparatus, 100 mL of toluene as a solvent, argon gas, 120 C for 24 h, and purified to obtain N-methylsilyl (trimethyl) imidazole type ionic liquid.
According to the analysis of related databases, 45676-04-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Hangzhou Normal University; Bai, Ying; Peng, Jiajian; Yang, Xioaling; Zhang, Fengxiang; Li, Jiayun; Xiao, Wenjun; (8 pag.)CN106380487; (2017); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem