Adding a certain compound to certain chemical reactions, such as: 693-98-1, name is 2-Methyl-1H-imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 693-98-1, name: 2-Methyl-1H-imidazole
Under a protection of N2, 0.25 mol of potassium carbonate, 0.5 mol of 2-methylimidazole and 0.6 mol of acrylonitrile were added to 60 mL of anhydrous methanol in a 250 ml three-neck round bottom flask, and the mixture was stirred under reflux in an oil bath at 60 C for 12 h. Complete reaction; After the reaction was stopped, the unreacted raw materials and methanol were removed by rotary evaporation, and dried under vacuum at 70 C for 24 hours to obtain a yellow transparent liquid. It is 1-nitrileethyl-2-methylimidazole. The yield was 82%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2-Methyl-1H-imidazole, and friends who are interested can also refer to it.
Reference:
Patent; Hebei University of Technology; Zhang Wenlin; Wang Yuxin; He Jiaming; Zhao Yongqi; Huo Yu; Li Chunli; (12 pag.)CN108976169; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem