In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 56248-10-3 as follows. SDS of cas: 56248-10-3
1 -(2-Hydroxypropyl)-4-Phenyl-1 H-imidazole-2-carbaldehyde In a closed vessel a slurry of 4-phenyl-1 H-imidazole-2-carbaldehyde (200 mg, 1.16 mmol) and sodium carbonate (60 mg, 0.6 mmol) in ethanol (4 mL) was treated with propylene oxide (170 muL, 2.4 mmol) and heated at 1000C for 3 h. The cooled solution was filtered and the solids washed with DCM. The volatiles were removed in vacuo to yield the crude title compound which was used without further purification (250 mg, 63%). LC-MS: m/z = 231.5 (MH+), tR = 0.41 min, method A
According to the analysis of related databases, 56248-10-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; H. Lundbeck A/S; WO2009/152825; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem