Some tips on 1H-Benzo[d]imidazole-2-carbaldehyde

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

3314-30-5, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3314-30-5, name is 1H-Benzo[d]imidazole-2-carbaldehyde, A new synthetic method of this compound is introduced below.

A mixture of (S)-(+)-2-(diphenylphosphine oxide)-1,1′-binaphthyl-2′-amine 6 (200 mg, 0.426 mmol) and 2-formyl-1H-benzoimidazole (187 mg, 1.278 mmol) in the presence of 4 A MS (0.85 g) in dry toluene (8 mL) was stirred at 110 ¡ãC for 14 h in a pressure tube.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Eliseenko, Sviatoslav S.; Liu, Fei; Tetrahedron; vol. 75; 4; (2019); p. 518 – 526;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem