Adding a certain compound to certain chemical reactions, such as: 53484-18-7, name is 1-Methyl-1H-benzo[d]imidazole-6-carboxylic acid, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 53484-18-7, Computed Properties of C9H8N2O2
Oxalyl chloride (42 mu, 0.47 mmol, 1.7 eq) was added dropwise to a mixture of 1- methyl-lH-benzo[d]imidazole-6-carboxylic acid (50 mg, 0.28 mmol, 1.0 eq) and DMF (2 mu, 0.03 mmol, 0.1 eq) in DCM (0.8 mL). The reaction was stirred at rt for 2 hrs. The reaction was concentrated under reduced pressure to give crude l-methyl-lH-benzo[d]imidazole-6- carbonyl chloride as a yellow residue that was used without further purification.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-1H-benzo[d]imidazole-6-carboxylic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ENANTA PHARMACEUTICALS INC; GRANGER, Brett; WANG, Gouqiang; SHEN, Ruichao; MA, Jun; XING, Xuechao; HE, Jing; HE, Yong; LONG, Jiang; WANG, Bin; OR, Yat, Sun; (108 pag.)WO2018/218044; (2018); A2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem