Electric Literature of 570-22-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 570-22-9 name is 1H-Imidazole-4,5-dicarboxylic acid, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
A mixture of CuCl2 (0.2 mmol, 26.9 mg), 4,5-H3imdc(0.1 mmol, 15.8 mg), and phen (0.1 mmol, 19.8 mg) in themolar ratio of 2:1:1 was dissolved in 4 mL distilled water and4 mL DMF (DMFDN,N0-dimethylformamide) and stirred30 min. Then, the mixture was transferred and sealed in10 mL glassflask heated at 85C for 96 h. After the samplewas cooled to room temperature, the crystals were washedwith distilled water and blue strip crystals werefiltered offand dried at room temperature. The yield of the blue crystalline product was 54% (based on Cu). Anal. Calcd forC17H10N4O4Cu: C, 51.28; H, 2.51; N, 14.08%. Found: C,51.13; H, 2.49; N, 14.02%. IR (KBr, cm1): 3687(w), 3045(m), 1683(m), 1572(s), 1474(s), 1428(s), 1238(m), 1107(m),995(w), 851(m), 779(w), 720(m), 675(w), 511(w).
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1H-Imidazole-4,5-dicarboxylic acid, and friends who are interested can also refer to it.
Reference:
Article; Zhang, Huijie; Zhou, Guangpeng; Fan, Ruiqing; Wang, Xinming; Yang, Yulin; Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry; vol. 46; 8; (2016); p. 1224 – 1235;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem