Electric Literature of 1072-63-5, These common heterocyclic compound, 1072-63-5, name is 1-Vinyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Typically, 1-vinylimidazole (5 g, 15 mmol) and an excess molar amount of 1-bromododecane (7 g, 7 mmol) were loaded into a 100 mL reactor. The mixture was stirred at room temperature overnight, followed at 60 C for 24 h. After cooling down, the reaction mixture was added dropwise into 250 mL of diethyl ether and white precipitate was formed. The precipitate was filtered off and washed with diethyl ether again and dried at room temperature until constant weight (95% yields). The formed solid was dissolved in 20 mL CH2Cl2 in a 50 mL round bottom flask, and aqueous HBF4 (50%) at a 1.1 + 1 M ratio was slowly dropped into the flask. After one week, [C12vim][BF4] was separated by extraction with distilled water. The organic layer was collected, dried over Na2SO4, filtered and the solvent removed in vacuum to give the product. (0007) [C12vim][Br]: 1H NMR (DMSO-d6, delta ppm): 9.53 (1H), 8.20 (1H), 7.93 (1H), 7.28 (1H), 5.95 (1H), 5.41 (1H), 4.18 (2H), 1.81 (2H), 1.23 (18H), 0.85 (3H). Anal. calculated for C17H31N2Br: C, 50.88; H, 10.95; N, 9.89. Found: C, 57.99; H, 9.35; N, 8.00. (0008) [C12vim][BF4]: 1H NMR (DMSO-d6, delta ppm): 9.45 (1H), 8.18 (1H), 7.91 (1H), 7.27 (1H), 5.93 (1H), 5.41 (1H), 4.17 (2H), 1.81 (2H), 1.25 (18H), 0.85 (3H). 19F NMR (DMSO-d6, delta ppm): -148.73. Anal. calculated for C17H31N2BF4: C, 49.69; H, 10.70; N, 9.66. Found: C, 59.15; H, 9.41; N, 7.85; Br, 0.
Statistics shows that 1-Vinyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 1072-63-5.
Reference:
Article; Pourjavadi, Ali; Doulabi, Malihe; Hosseini, Seyed Hassan; Polymer; vol. 53; 25; (2012); p. 5737 – 5742;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem