Reference of 21252-69-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 21252-69-7, name is 1-Octyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
To a three-necked flask equipped with a stirrer and a thermometer, 1.44 g (8.0 mmol) of N-octylimidazole, 0.56 g (4.4 mmol) 1,3-dichloro-2-propanol, stirring at 115 ° C ~ 125 ° C reaction, TLC follow the progress of the reaction, about 8 ~ 12h after the end of the reaction. The crude product was recrystallized from a mixed solvent of chloroform and ethyl acetate, A white powdery solid was obtained 1,1 ‘-dioctyl-3,3′(2-hydroxy-1,3-propylene) imidazole hydrochloride (1.02 g, yield 52.1percent).
The synthetic route of 1-Octyl-1H-imidazole has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Qiqihar university; Wang, LiYan; Deng, QiGang; Zheng, YongJie; Huo, shichao; Liu, Jia; Sun, zhu; (10 pag.)CN103951702; (2016); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem