Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 104619-51-4, name is Di(1H-imidazol-1-yl)methanimine, A new synthetic method of this compound is introduced below., COA of Formula: C7H7N5
To a stirred solution of 2-amino-4- (pentafluorosulfanyl) phenol (40) (70 mg, 0.30 mmol) in CH 3CN (1 mL) was added di (1H-imidazol-1-yl) methanimine (96 mg, 0.60 mmol) in one portion at 20 . The reaction mixture was stirred at 80 for 6 h. The solvent was evaporated and the residue was purified by column chromatography (silica gel, petroleum ether/EtOAc 10: 1-2: 1) to afford the titled compound IV (56 mg, 72) as a white solid. [0347] 1H NMR (400MHz, DMSO-d6) delta 7.85 (s, 2 H) , 7.68 (s, 1 H) , 7.52 (s, 1 H) [0348] MS (ESI) : [M+H +] 260.8.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; XW LABORATORIES INC.; XW LABORATORIES, INC.; XIANG, Jia-Ning; XU, Xuesong; ZHOU, Wei; (123 pag.)WO2018/176343; (2018); A1;,
Imidazole – Wikipedia,
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