Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 17289-20-2, name is Methyl 1-methyl-1H-imidazole-5-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C6H8N2O2
To the solution of commercially available 4.3 g methyl 3-methylimidazole-4-carboxyIate in 100 mL THF at 23 C was added 7.4 g lithium tertbutoxide and reaction mixture was stirred at 23 C for 15 min. Then, 10.9 g N-bromosuccinimide (NBS) was added and reaction mixture was stirred at 23 C for additional 12 h. Reaction mixture was quenched with water and was basified with sat. NaHCC>3 solution to pH 14. The compound was extracted with EtOAc (20 mL x 3), combined organic layer was dried over Na2S04and concentrated under reduced pressure to get crude compound which was purified by column chromatography over silica gel using 30 % EtOAc in />heptane as an eluent to afford the title compound as off white solid (1.8 g; 27.0% yield).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 17289-20-2.
Reference:
Patent; BASF SE; GOCKEL, Birgit; SOERGEL, Sebastian; KOERBER, Karsten; (152 pag.)WO2019/137995; (2019); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem