Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6160-65-2, name is 1,1′-Thiocarbonyldiimidazole, This compound has unique chemical properties. The synthetic route is as follows., Safety of 1,1′-Thiocarbonyldiimidazole
A solution of (2R)-3-PHENYL-1-PIVALOYLOXY-2-PROPYL amine (19-1, LMMOL) and ET3N (1 mmol) in DMF (1 mL) was added dropwise into the pre-dissolved solution of 1,1- thiocarbonyl diimidazole (1.2 mmol) in DMF (2 mL) at 50 C over 1 min. The mixture was stirred for 1 min. at 50 C and then for 10 min. at room temperature. The mixture was directly purified by column chromatography using EtOAc: hexanes (1: 5) as eluant to afford (2R)-3-phenyl-1-pivaloyloxy-2-propyl isothiocyanate (19-3, SU-684). 89% yield, colorless oil. H NMR (CDC13) 5 7.15-7. 35 (M, 5 H), 4.22 (dd, 1 H, J= 2. 7,10 Hz), 4.02-4. 12 (m, 2 H), 2.94 (d, 2 H, J= 6. 3 HZ), 1.25 (s, 9 H)
According to the analysis of related databases, 6160-65-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DIGITALBIOTECH CO., LTD.; WO2005/3084; (2005); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem