37052-78-1, Name is 5-Methoxy-1H-benzo[d]imidazole-2-thiol, 37052-78-1, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows.
EXAMPLE 3 F Preparation of 2 -(4 -morpholino-3 -chloro-2 -pyridylmethylthio)-5 -methoxy-(1H)-benzimidazole 5 N Sodium hydroxide (5.68 ml) was added dropwise to a stirred solution of 4 -morpholino-3 -chloro-2 -chloromethylpyridine hydrochloride (3.66 g) and 5 -methoxy-2 -mercaptobenzimidazole (2.33 g). After standing overnight the solution was evaporated under reduced pressure and the residue triturated with water. The solid thus obtained was recrystallized from ethanol to give 2 -(4 -morpholino-3 -chloro-2 -pyridyl-methylthio)-5 -methoxy-(1H)-benzimidazole, 4.38 g, m.p. 124-25.
Statistics shows that 5-Methoxy-1H-benzo[d]imidazole-2-thiol is playing an increasingly important role. we look forward to future research findings about 37052-78-1.
Reference:
Patent; SmithKline & French Laboratories Limited; US5250527; (1993); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem