583-39-1, A common compound: 583-39-1, name is 2-Mercaptobenzimidazole, belongs to imidazoles-derivatives compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
A mixture of 1H-benzo[d]imidazole-2(3H)-thione (III, 21 mg, 0.2 mmol) and [RuII(eta6-p-cymene)(PPh3)(CH3CN)Cl]PF6 (5, 144 mg, 0.2 mmol) in CH2Cl2 (20 mL) was stirred for 3 h at room temperature. The solvent was concentrated to a small amount (ca. 3 mL) and the product was precipitated by addition of pentane (ca. 20 mL). The orange yellow powder was filtered, washed with pentane (2 ¡Á 5 mL) and dried in vacuo. Yield: 146 mg (88%), m.p. 200 C (decomp.). Elemental analysis (%) calcd. for C35H35ClF6N2P2RuS*0.5CH2Cl2: C 48.97, H 4.17, N 3.22, S 3.68, found: C 49.02, H 4.38, N 3.29, S 3.74. 1H-NMR (CDCl3): delta = 11.46 (s, 2H, NH),7.58-7.62 (m, 6 H, PPh3), 7.34-7.37 (m, 10H, PPh3/Ar-thione), 7.24-7.27 (m, 3H, PPh3), 5.47 (d, J = 6 Hz, 1 H, H-Ar), 5.31 (d, J = 6 Hz, 1 H, H-Ar), 5.21 (d, J = 6 Hz, 1 H, H-Ar), 5.06 (d, J = 6 Hz, 1 H, H-Ar), 2.81-2.89 (m, 1 H,CH(CH3)2), 1.90 (s, 3 H, CH3), 1.18 (d, J = 7 Hz, 3H, CH(CH3)2), 1.16 (d, J = 7 Hz, 3H, CH(CH3)2) ppm. 13C{1H}-NMR (CDCl3): delta = 163.8 (C=S), 134.1 (C-PPh3), 132.0 (C-PPh3), 131.6 (C-Arthione), 131.1 (C-Arthione), 130.8 (C-PPh3), 128.4 (C-PPh3), 124.6 (C-Arthione), 116.5 (C-Ar), 111.7 (C-Arthione), 101.1 (C-Ar), 92.0 (d, J = 2 Hz, C-Ar), 91.3 (d, J = 4 Hz, C-Ar), 90.0 (d, J = 2 Hz, C-Ar), 89.0 (d,J = 4 Hz, C-Ar), 30.5 (CH(CH3)2), 22.5(CH(CH3)2), 21.4 (CH(CH3)2), 17.6 (CH3) ppm. 31P{1H}-NMR(CDCl3): delta = 29.5 (s, PPh3), -144.2 (sept, PF6) ppm.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Mercaptobenzimidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Hanif, Muhammad; Nawaz, Muhammad Azhar Hayat; Babak, Maria V.; Iqbal, Jamshed; Roller, Alexander; Keppler, Bernhard K.; Hartinger, Christian G.; Molecules; vol. 19; 6; (2014); p. 8080 – 8092;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem