Related Products of 641571-11-1, These common heterocyclic compound, 641571-11-1, name is 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Method D[98] A pale yellow solid final compound (15.3g, yield 71%) was obtained by reacting3-(4-methyl-imidazole-l-yl)-5-trifluoromethyl-phenylamine (1Og, 41.46mmol) with 3-(4-imidazole-l-yl-pyrimidine-2-yl amino)-4-methyl-benzoic acid phenyl ester in a similar manner as described in Method A of Example 1, except that 3-(4-imidazole-l-yl-pyrimidine-2-yl amino)-4-methyl-benzoic acid phenyl ester (16.9g, 45.60mmol) was used, instead of 4-methyl-3-(4-thiazole-2-yl-pyrimidine-2-yl amino)benzoic acid ethyl ester.
The synthetic route of 641571-11-1 has been constantly updated, and we look forward to future research findings.