Electric Literature of 1402838-08-7,Some common heterocyclic compound, 1402838-08-7, name is 2-(1-Trityl-4-imidazolyl)benzaldehyde, molecular formula is C29H22N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
5-(2-(Dimethoxyphosphoryl)acetyl)-1H-carbazole-1-carboxylic acid tert-butyl ester (0304-105) (375 mg, 1.0 mmol, 1.4 equiv),2-(1-trityl-1H-imidazol-4-yl)benzaldehyde (0105-1) (300 mg, 0.73 mmol, 1.0 equiv) andCesium carbonate (900 mg, 2.8 mmol, 3.8 eq.)Added to 60 ml of isopropanol,The reaction was stirred at room temperature overnight, concentrated under reduced pressure, ethyl acetate and water were added,The layers were separated, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give the product as a yellow solid 5-(3-(2-(1-triphenylmethyl-1H-imidazole-4-(phenyl)acryloyl)-1H-carbazole-1-carboxyl
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(1-Trityl-4-imidazolyl)benzaldehyde, its application will become more common.