These common heterocyclic compound, 492-98-8, name is 1H,1’H-2,2′-Biimidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. name: 1H,1’H-2,2′-Biimidazole
A methanol solution (10 mL) of Cu(ClO4)2¡¤6H2O (0.33 g, 2 mmol) was initially reacted with acetylacetone (0.02 g, 2 mmol) treated with NaOH (0.040 g, 1.0 mmol) in water (10 mL) under magnetic stirring at room temperature. After 30 min, a 20 mL methanolic solution of the biimidazole (0.15 g, 2 mmol) was added to the solution and the resulting mixture was stirred for 2 h at room temperature. The green colored solid was isolated and washed with cold aqueous methanol and finally dried over P4O10 (Yield: 67%).
The synthetic route of 1H,1’H-2,2′-Biimidazole has been constantly updated, and we look forward to future research findings.
Reference:
Article; Nagasubramanian, Soundarajan; Thamilarasan, Vijayan; Jayamani, Arumugam; Kang, Sung Kwon; Kim, Young-Inn; Sengottuvelan, Nallathambi; Bulletin of the Korean Chemical Society; vol. 34; 6; (2013); p. 1875 – 1878;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem