Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 60-56-0, Name is 1-Methyl-1H-imidazole-2(3H)-thione, molecular formula is C4H6N2S, belongs to imidazoles-derivatives compound, is a common compound. In a patnet, author is Li, H, once mentioned the new application about 60-56-0, COA of Formula: C4H6N2S.
Remarkable rate acceleration of water-promoted nucleophilic substitution of Baylis-Hillman acetate: a facile and highly efficient synthesis of N-substituted imidazole
Without additional reagents, the Baylis-Hillman acetates 2 underwent nucleophilic Substitution reaction with imidazole readily in aqueous THF solution to afford the corresponding N-substituted imidazole derivatives 3 in good to excellent yields. Moreover, the reaction between the in situ generated DABCO salt of Baylis-Hillinan acetates 4 and imidazole occurs in aqueous THF providing the S(N)2 type products 5. The simpler operational procedure, better stereoselectivity and higher efficiency over conventional method make the present protocol practical for the preparation of imidazole derivatives. (c) 2005 Elsevier Ltd. All rights reserved.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 60-56-0. The above is the message from the blog manager. COA of Formula: C4H6N2S.