Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, HPLC of Formula: C4H6N2S60-56-0, Name is 1-Methyl-1H-imidazole-2(3H)-thione, SMILES is S=C1NC=CN1C, belongs to imidazoles-derivatives compound. In a article, author is Jayabharathi, Jayaraman, introduce new discover of the category.
A study on the binding interaction between the imidazole derivative and bovine serum albumin by fluorescence spectroscopy
The interaction between the imidazole derivative 2-(2,4-difluorophenyl)-1-phenyl-1H-imidazo[4,5-f] [1,10]phenanthroline (dfppip) and bovine serum albumin (BSA) was investigated by fluorescence and UV-vis absorbance spectroscopy. From the experimental results, it was found that the imidazole derivative has strong ability to quench the intrinsic fluorescence of BSA by forming complexes. Electrostatic interactions play an important role to stabilize the complex. The binding constants and the number of binding sites have been determined in detail. The distance (r) between the donor and the acceptor was obtained according to fluorescence resonance energy transfer (FRET). Conformational changes of BSA were observed from synchronous fluorescence spectroscopy. The effect of metal ions such as Cu2+, Zn2+, Ca2+, Mg2+, Ni2+, Co2+ and Fe2+ on the binding constants between the imidazole derivative and BSA were also studied. (C) 2011 Elsevier B.V. All rights reserved.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 60-56-0. HPLC of Formula: C4H6N2S.