The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 23996-25-0, Name is 2-Ethyl-4-methyl-1H-imidazole-1-propanenitrile, SMILES is CCC1=NC(C)=CN1CCC#N, in an article , author is Arai, Nobumichi, once mentioned of 23996-25-0, Recommanded Product: 23996-25-0.
Palladium-catalyzed intramolecular CH arylation of five-membered N-heterocycles
Intramolecular CH arylation of imidazole derivatives is carried out in the presence of a palladium catalyst to form fused heteroaromatic compounds. The reaction of imidazole with 2-iodobenzyl bromide with NaH gives the cyclization precursor in an excellent yield. This then undergoes a palladium-catalyzed intramolecular CH arylation at 100 degrees C to form 5H-imidazo[5,1-a]isoindole in 78% yield.
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