Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 616-47-7, name is 1-Methyl-1H-imidazole, A new synthetic method of this compound is introduced below., name: 1-Methyl-1H-imidazole
General procedure: [BSTMG][HSO4]: 1,1,3,3-tetramethylguanidine (0.2 mol) and 1,4-butane sultone (0.2 mol) were charged into a 250 mL round bottom flask equipped with a reflux condenser. Then the mixtures were stirred at 353 K for 7 h. The obtained white solid zwitterion was washed several times with toluene to remove non-ionic residues and dried in vacuum. After that, a stoichiometric amount of sulphuric acid (0.2 mol) was added dropwise and the mixture was stirred for 10 h at 343 K. A kind of viscous ionic liquid phase was obtained and was washed by ether for several times. The ionic liquid was dried in vacuum for 2 h. The ionic liquids [BSTMG][CF3SO3], [BSTMG][CF3CO2], [BSPy][HSO4], [BSIMI][HSO4]and [BSEt3N][HSO4] were prepared by the same procedure.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Wu, Li; Li, Zhen; Wang, Fang; Lei, Min; Chen, Jing; Journal of Molecular Catalysis A: Chemical; vol. 379; (2013); p. 86 – 93;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem