Adding a certain compound to certain chemical reactions, such as: 28890-99-5, name is 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 28890-99-5, COA of Formula: C13H9N3
d) Compound 8-3 (3.0 g, 8.10 mmol), benzimidazolo[1,2-a]benzimidazole (1.85 g, 8.91mmol), and potassium phosphate (1.96 g, 16.2 mmol) were added to NMP (30 mL). Themixture was stirred at 190 C for 17 h. In addition, potassium phosphate (3.92 g, 32.4 mmol) was added there, and the mixture was stirred at the same temperature for 27 h. Af8-2 ter reaction mixture was cooled at room temperature, it was diluted with water to give asolid. The solid was collected by filtration, and it was washed with 300 mL of MeOH. Thecrude product was purified by by column chromatography on silica gel eluting with CH2CI2to yield 4.7 g (78%) of compound (B-29) as a white solid. LC-MS (m/z) 745.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole, and friends who are interested can also refer to it.
Reference:
Patent; IDEMITSU KOSAN CO., LTD.; NISHIMAE, Yuichi; KOHLSTEDT, Julia; SCHAeFER, Thomas; NAGASHIMA, Hideaki; (114 pag.)WO2016/97983; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem