Synthetic Route of 3304-70-9,Some common heterocyclic compound, 3304-70-9, name is Dimethyl 4,5-imidazoledicarboxylate, molecular formula is C7H8N2O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a solution of dimethyl 1H-imidazole-4,5-dicarboxylate (1.58g) in water (15mL), was added bromine (4.11g). The mixture was stirred at 60C for Ihr.The solvent was evaporated in vacuo and the residue was triturated with ether to give the target compound (2.35g) as a solid.NMR (DMSO-d6) : d 3.81(6H, s).MASS m/z : 286 (M-l).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Dimethyl 4,5-imidazoledicarboxylate, its application will become more common.
Reference:
Patent; FUJISAWA PHARMACEUTICAL CO., LTD.; WO2004/108730; (2004); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem