Adding a certain compound to certain chemical reactions, such as: 56248-10-3, name is 5-Phenyl-1H-imidazole-2-carbaldehyde, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 56248-10-3, category: imidazoles-derivatives
In a closed vessel a slurry of 4-phenyl-1H-imidazole-2-carbaldehyde (200 mg, 1.16 mmol) and sodium carbonate (60 mg, 0.6 mmol) in ethanol (4 mL) was treated with propylene oxide (170 muL, 2.4 mmol) and heated at 100 C. for 3 h. The cooled solution was filtered and the solids washed with DCM. The volatiles were removed in vacuo to yield the crude title compound which was used without further purification (250 mg, 63%). LC-MS: m/z=231.5 (MH+), tR=0.41 min, method A
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Phenyl-1H-imidazole-2-carbaldehyde, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; H. LUNDBECK A/S; US2010/16303; (2010); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem