Ribosidation of 4-amino-5-imidazolecarboxamide by Escherichia coli was written by Ben-Ishai, R.;Bergmann, Ernst D.;Volcani, B. E.. And the article was included in Nature (London, United Kingdom) in 1951.Related Products of 26832-08-6 This article mentions the following:
Evidence is presented for the conversion of 4-amino-5-imidazolecarboxamide (I) by E. coli into a glycoside. The supernatant from a cell suspension of E. coli B, incubated with the hydrochloride of I in 0.066 M phosphate buffer, contained a growth-enhancing component for a purine-requiring E. coli mutant, which was more effective than I. The supernatant was lyophilized, concentrated, chromatographed on paper with 5% KH2PO4 in iso-AmOH, and developed by diazotization. Two distinct spots were obtained; Rf for the unknown was 0.63, and for the HCl of I 0.68. A pos. orcinol test and a color reaction with diphenylamine, exceeding that for the blank, indicated the presence of desoxyribose. The ultraviolet spectrum for the unknown had an absorption maximum at 2600 A. The ultraviolet maximum for the hydrochloride of I was 2680 A. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Related Products of 26832-08-6).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Related Products of 26832-08-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem