A New Class of Singlet Carbene Ligands was written by Alcarazo, Manuel;Suarez, Rosa M.;Goddard, Richard;Fuerstner, Alois. And the article was included in Chemistry – A European Journal in 2010.Product Details of 3012-80-4 This article mentions the following:
The synthesis of a series of singlet carbene ligands based on vinyl phosphonium (I; R = Ph, 2-pyridylphenyl, cyclohexyl, dimethylamino) and benzimidazolium salts (II) are reported. Deprotonation with potassium hexamethyldisilazide (KHMDS) yields a resonance form which can be described as a push-pull cumulene or as a zwitterionic form. The corresponding gold and rhodium complexes were obtained through treatment I or II with KHMDS at -78° followed by addition of (Me2S)AuCl, [Rh(CO)2Cl]2 or [Rh(COD)Cl]2 (COD = η4-1,5-cyclooctadiene). Representative examples of the new complexes were determined by x-ray crystallog. Both I and II are readily accessible precursors for a new class of singlet carbene ligands having appreciable donor qualities equal to or greater than those of traditional N-heterocyclic carbenes. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Product Details of 3012-80-4).
1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Product Details of 3012-80-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem