Dialkylimidazolium dimethyl phosphates as solvents and catalysts for the Knoevenagel condensation reaction was written by Zicmanis, Andris;Anteina, Liene. And the article was included in Tetrahedron Letters in 2014.Reference of 21252-69-7 This article mentions the following:
The reaction between benzaldehyde and Et cyanoacetate is investigated in 1,3-dialkylimidazolium salts as solvents. The impact of both ions in these ionic liquids on the yield of the condensation reaction product is examined Potentiometric titrations are employed for quant. anal. of the best ionic liquids, revealing these to be 1,3-dialkylimidazolium di-Me phosphates. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Reference of 21252-69-7).
1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Reference of 21252-69-7
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem