Photoisomerization of indazoles to benzimidazoles was written by Tiefenthaler, H.;Dorscheln, W.;Goth, H.;Schmid, H.. And the article was included in Tetrahedron Letters in 1964.SDS of cas: 4887-83-6 This article mentions the following:
Indazole, 3-, 4-, 5-, 6-, or 7-methyl-, and 6-methoxyindazole irradiated with uv light (high pressure Hg lamp) in MeOH, EtOAc, or dioxane 3-20 hrs. at 25-90掳 were irreversibly converted in 9-31% yields to the corresponding benzimidazoles. The influence of solvent, reaction time, and temperature was tabulated. No isomerization was noted for 3-Ph-, 5-MeO-, 5-Cl-, and 6-Cl-substituted imidazoles. Pyrazole on irradiation in dioxane gave 12% imidazole. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6SDS of cas: 4887-83-6).
7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.SDS of cas: 4887-83-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem