The infrared spectra of some simple benzimidazoles was written by Morgan, K. J.. And the article was included in Journal of the Chemical Society in 1961.Related Products of 4887-83-6 This article mentions the following:
The spectra of solid specimens of the simple alkyl and perfluoroalkylbenzimidazoles are characterized by a series of strong, broad bands in the region 2400-3200 cm.-1 They show no band in the region normally associated with the simple N-H stretching frequency. The alkyl and perfluoroalkyl groups are 2-Me, Et, 2-Pr, 2-iso-Pr, 4-Me, 5-Me, 2,5-Me2, 2-CF3, 2-C2F5, 2-C3F7, 4-CF3, 5-CF3, 2-Me-4-CF3, 4-Me-2-CF3, 4-Me-2-Pr, 2,4-(CF3)2, 2,5-(CF3)2, 2-Me-4,5-(CF3)2 2,4,5-(CF3聽3, 5-MeO-2-CF3, 4,5,6,7-F4-2-CF3. Strong bands near 2400-3200 cm.-1 are ascribed to a strong H bond of the type N-H. . .N, showing proton transfer. The position of the N-H bands of the spectra of solutions of benzimidazoles is similar to that found for pyrroles and indoles. The bands show typical displacements when tetrachloroethylene replaces CH2Cl2 as solvent. Small increases in the frequency of the alkyl derivatives and large decreases in frequency of the perfluoroalkyl compounds diminish as the orientation of substitution varies 2 > 4 鈮?5. These shifts are mainly due to induction, and there is little H bonding to adjacent F atoms. Compounds with perfluoralkyl substituents show more intense absorption, giving higher values of extinction coefficients and broader bands. Spectra of perimidine, 2-methyl-, 2-ethyl-, and 2-propylperimidine show broad banded absorption from 2400 to 3200 cm.-1 In solution spectra these bonded IV-H bands are replaced by sharp bands near 3400 cm.-1 Benzimi- dazole-2-acetic acid and difluoroacetic acid have spectra indicating a strongly bonded carbonyl group and discrete OH and NH groups. In 尾-(2-benzimidazolyl)propionic acid the carbonyl is replaced by a broad band at 1550 cm.-1 and the C-O stretching frequency is displaced to 1410 cm.-1 This compound is regarded as zwitterionic. 2-Benzimidazolecarboxylic acid has a bonded carbonyl group but shows no discrete OH or amino bonds. 5-Trifluoromethyl-2-benzimidazolecarboxylic acid is similar, and a low carbonyl frequency suggests that the 4-trifluoromethyl analog is best written as a nonbonded compound In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Related Products of 4887-83-6).
7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 4887-83-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem