Optimized one-step synthesis and characterization of 1-methyl-4,5-dinitro-1H-imidazole was written by Luo, Jin;Liu, Yu-Cun;Liu, Yan;Chai, Tao. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2017.Recommanded Product: 1-Methyl-4-nitroimidazole This article mentions the following:
Highly pure 1-methyl-4,5-dinitro-1H-imidazole was obtained from N-methylimidazole in 79% yield. The process was optimized with regard to nitrating mixture composition and the ratio of N-methylimidazole and nitrating mixture The effects of reaction temperature, time, and the rate of nitrating mixture addition were analyzed. The endothermic peak due to melting was obvious on the DSC curve at 75掳, decomposition started at about 250掳, and the main exothermic decomposition peak was at 278.5掳, which indicated that this compound has good thermal stability. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 1-Methyl-4-nitroimidazole).
1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Recommanded Product: 1-Methyl-4-nitroimidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem