Vascular action of some imidazoles was written by Loeper, M.;Mougeot, A.;Aubertot, R.. And the article was included in Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales in 1934.SDS of cas: 26832-08-6 This article mentions the following:
The action of 4-methylimidazole, 4-methoxyimidazole, imidazole-4-formamide and diarabinotetrahydroxybutylimidazole on snail hearts, isolated arteries and live dogs was studied. The first 2 are hypertensive. Similar experiments by others with various imidazole derivatives are reviewed. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6SDS of cas: 26832-08-6).
1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.SDS of cas: 26832-08-6
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem