A visible-light-activated rhodium complex in enantioselective conjugate addition of 伪-amino radicals with Michael acceptors was written by Lin, Shao-Xia;Sun, Gui-Jun;Kang, Qiang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Synthetic Route of C6H8N2O This article mentions the following:
We report an efficient enantioselective conjugate addition of photogenerated 伪-amino radicals to Michael acceptors catalyzed by a newly prepared chiral-at-metal rhodium complex. This protocol shows that a single Rh(III) complex can serve not only as a Lewis acid but also as a photoredox catalyst to control the stereoselectivity during the bond formation. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Synthetic Route of C6H8N2O).
1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Synthetic Route of C6H8N2O
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem