Gaba, Rekha et al. published their research in Journal of Molecular Liquids in 2017 | CAS: 35487-17-3

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C4H7ClN2

Hydration properties of glycylglycine in aqueous ionic liquid solutions at different temperatures: Volumetric and acoustic approach was written by Gaba, Rekha;Pal, Amalendu;Sharma, Dinkar;Amirchand Khajuria, Deepika. And the article was included in Journal of Molecular Liquids in 2017.Synthetic Route of C4H7ClN2 This article mentions the following:

The apparent molar volume and isentropic compression of glycylglycine in aqueous 1-methylimidazolium chloride, [mim][Cl], 1-ethyl-3-methylimidazolium chloride [C2mim][Cl], and 1-methyl-3-octylimidazolium chloride [C8mim][Cl] solutions have been calculated from the measured exptl. data on d. and speed of sound at temperature, T = 288.15, 298.15 and 308.15 K. The apparent molar volumes at infinite dilution, V0蠒 and the apparent isentropic molar compression at infinite dilution K0蠒聽,聽S, were also calculated Furthermore, apparent sp. volumes, apparent molar expansivity, E0蠒, Hepler’s constant values, (((鈭?em>E0蠒)/(鈭?em>T)))P and hydration numbers, nH, have been evaluated to support the conclusions obtained from the volumetric and acoustic studies. The Hepler’s constant values were found neg. which indicating the peptide under study is predominantly a structure breaker due to hydrophobic hydration of small peptide in aqueous ionic liquid In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Synthetic Route of C4H7ClN2).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C4H7ClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem