Determination of Missing Crystal Structures in the 1 Alkyl-3-methylimidazolium Hexafluorophosphate Series: Implications on Structure-Property Relationships was written by Endo, Takatsugu;Masu, Hyuma;Fujii, Kozo;Morita, Takeshi;Seki, Hiroko;Sen, Sabyasachi;Nishikawa, Keiko. And the article was included in Crystal Growth & Design in 2013.Electric Literature of C7H13ClN2 This article mentions the following:
The authors have performed single crystal X-ray diffraction analyses of two 1-alkyl-3-methylimidazolium hexafluorophosphate ([Cnmim]-PF6) salts, [C1mim]-PF6, and [C3mim]-PF6. The thermodynamically metastable crystalline phase (尾 phase) of the former was obtained by crystallization from the melt in a capillary for the crystallog. anal. Both the cation and the anion in the 尾 phase of [C1mim]-PF6 show higher point group symmetry than those in the stable 伪 phase. This result is shown to be consistent with the fact that the m.p. of the 尾 polymorph (314 K) is significantly lower than that of the 伪 polymorph (364 K). The crystal structure of [C3mim]-PF6 seems to be typical of that characteristic of the crystals of imidazolium-based room temperature ionic liquids The cation conformation is the one in between those characteristic of the crystal structures of [C2mim]-PF6 and [C4mim]-PF6. When taken together, all crystallog. data for the [Cnmim]-PF6 series (n = 1-4) demonstrate the influence of the alkyl chain length dependence on structural packing in these salts. The free volume fractions for these structures are calculated and compared to the lattice energy simply based on formula unit volume It is shown that the difference in the alkyl chain length of the imidazolium cations does not monotonically change with the lattice energy of the crystal structure, and the latter also depends on the packing efficiency of the constituent ions in the structure. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Electric Literature of C7H13ClN2).
1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Electric Literature of C7H13ClN2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem