Synthesis of halogen derivatives of N-methylimidazole was written by El Borai, M.;Moustafa, A. H.;Anwar, M.;Abdel Hay, F. I.. And the article was included in Polish Journal of Chemistry in 1981.Recommanded Product: 4-Bromo-1-methylimidazole This article mentions the following:
1-Methylimidazole (I) was converted to 2-halo-, 2,5-dihalo-, 5-halo-, 2,4-dihalo-, 4,5-dihalo-, 4-halo-, and 2,4,5-trihalo-1-methylimidazoles. I was treated with BuLi and Br2 to give 2-bromo-1-methylimidazole. The reaction of I with N-bromosuccinimide gave 5-bromo-1-methylimidazole. I reacted with iodine and HIO3 to give 4,5-diiodo-1-methylimidazole. In the experiment, the researchers used many compounds, for example, 4-Bromo-1-methylimidazole (cas: 25676-75-9Recommanded Product: 4-Bromo-1-methylimidazole).
4-Bromo-1-methylimidazole (cas: 25676-75-9) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Recommanded Product: 4-Bromo-1-methylimidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem