An efficient ICT based fluorescent turn-on dyad for selective detection of fluoride and carbon dioxide was written by Ali, Rashid;Razi, Syed S.;Gupta, Ramesh C.;Dwivedi, Sushil K.;Misra, Arvind. And the article was included in New Journal of Chemistry in 2016.Name: 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid This article mentions the following:
A new intramol. charge transfer (ICT) based fluorescent turn-on ratiometric probe 2 (D-蟺-A type) has been designed and synthesized by bridging imidazole (donor, D) and benzothiazole (acceptor, A) moieties through a Ph ring. The photophys. behavior of probe 2 in solvents of different polarities and at different pH values has been investigated. Upon interaction with different types of anions probe 2 showed selective high affinity for fluoride anions (F–) in aqueous DMSO (20%) solution The ratiometric fluorescence turn-on behavior displayed by 2 with F– is attributed to changes in the ICT process. Job’s plot anal. revealed a 1 : 1 binding stoichiometry for 2 + F– interactions with a high binding constant and detection sensitivity (30 ppb). Moreover, a solution of 2 + F– enabled the detection of CO2 (鈭?00 ppb; 2.29 渭M) through enhanced emission. The mode of interaction has been confirmed by 1H NMR titration studies which suggested the deprotonation of the -NH fragment of an imidazolyl unit in the presence of F–. In the experiment, the researchers used many compounds, for example, 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5Name: 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid).
4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid (cas: 5496-35-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Name: 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoic acid
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem