Interaction of Imidazolium-Based Room-Temperature Ionic Liquids with DOPC Phospholipid Monolayers: Electrochemical Study was written by Galluzzi, Massimiliano;Zhang, Shengwen;Mohamadi, Shahrzad;Vakurov, Alexander;Podesta, Alessandro;Nelson, Andrew. And the article was included in Langmuir in 2013.Related Products of 404001-48-5 This article mentions the following:
To test the biocompatible character of room-temperature ionic liquids (ILs), the interaction of various ILs with biol. membrane (biomembrane) models was studied. Dioleoyl phosphatidylcholine (DOPC) adsorbed on a Hg electrode forms an impermeable defect-free monolayer which is a well established biomembrane model, prone to be studied by electrochem. techniques. The authors have monitored the modifications of the Hg supported monolayer caused by ILs using rapid cyclic voltammetry (RCV), a.c. voltammetry (ACV), and electrochem. impedance spectroscopy (EIS). Imidazolium-based ILs were studied whose interaction highlighted the role of anion and lateral side chain of cation during the interaction with DOPC monolayers. The hydrophobic and lipophilic character of the IL cations is a primary factor responsible for this interaction. Hg-supported monolayers provide an accurate anal. of the behavior of ILs at the interface of a biomembrane leading to a comprehensive understanding of the interaction mechanisms involved. At the same time, these experiments show that the Hg-phospholipid model is an effective toxicity sensing technique as shown by the correlation between literature in vivo toxicity data and the data. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Related Products of 404001-48-5).
3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 404001-48-5
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem