Month: January 2023

The effects of cationic type ionic liquids on methane hydrate formation was written by Lu, Cui-ying. And the article was included in Advanced Materials Research (Durnten-Zurich, Switzerland) in 2014.Synthetic Route of C7H13ClN2 This article mentions the following:

The article has studied the effects of ionic liquids on the induction time of methane hydrate formation under different mass concentrations, temperatures and pressures. The results show: all the tested ionic liquids can postpone the induction time of hydrate forming. Among them, imimidazolium-based ones have the strongest ability; The concentrations of ionic liquids also have strong effects on the induction time, and 0.5% is optimal. In addition the inhibiting abilities of ionic liquid on the induction time change with different pressures and temperatures, but not obviously. In the experiment, the researchers used many compounds, for example, 1-ethyl-2,3-dimethylimidazolium chloride (cas: 92507-97-6Synthetic Route of C7H13ClN2).

1-ethyl-2,3-dimethylimidazolium chloride (cas: 92507-97-6) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Synthetic Route of C7H13ClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Evidence of Reversible N-H Exchange in a Three-Coordinate Amidozinc Complex. Syntheses and Structures of 1-Methyl-2-((N-tert-butylamino)methyl)benzimidazole Complexes of Zinc was written by Chinn, Mitchell S.;Chen, Jiazhong. And the article was included in Inorganic Chemistry in 1995.Quality Control of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde This article mentions the following:

1-Methyl-2-((N-tert-butylamino)methyl)benzimidazole (HL) reacts with 1 equiv of Zn[N(SiMe₃)₂]₂ in nonpolar solvents (benzene, toluene) yielding planar, 3-coordinate [ZnL(N(SiMe₃)₂)] (3) and HN(SiMe₃)₂. Compound 3 was characterized by ¹H and ¹³C NMR spectroscopy, elemental anal., and x-ray crystallog. The crystal structure of this complex at -100° (monoclinic, space group P2₁/n, a 8.468(2), b 18.700(4), c 15.551(2) Å, β 98.10(2)°, Z = 4, R = 4.43%, R_w = 5.35%) shows two short, equivalent amidozinc bonds of 1.874(4) Å and 1.887(4) Å and a longer Zn-N coordinate covalent bond of 2.067(4) Å to the benzimidazole N atom. No evidence of Zn^–:N⁺ double bond character is found even though a N lone pair and an empty, p-like Zn orbital are geometrically arranged for favorable overlap. Magnetization transfer studies show reversible, degenerate exchange between 3 and HL at 40°. Compound 3 undergoes rapid, irreversible protonolysis with HNMe₂ to produce HL, HN(SiMe₃)₂, and a white precipitate Addition of HL to a Et₂O solution of ZnCl₂ immediately forms a white precipitate of [ZnLCl₂] (2). Single crystals of 2 were grown from CH₂Cl₂ solutions The mol. structure of 2, determined by x-ray crystallog. at -100° (monoclinic, space group P2₁/n, a 7.622(2), b 14.378(3) Å, c 14.476(3) Å, β 104.91(2)°, Z = 4, R = 3.14%, R_w = 3.61%), shows the Zn atom in a distorted tetrahedral environment. Bonding between Zn and N atoms in four-coordinate 2 and three-coordinate 3 is compared. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Quality Control of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Quality Control of 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Nanocage formation and structural anomalies in imidazolium ionic liquid glasses governed by alkyl chains of cations was written by Bakulina, Olga D.;Ivanov, Mikhail Yu.;Prikhod’ko, Sergey A.;Pylaeva, Svetlana;Zaytseva, Irina V.;Surovtsev, Nikolay V.;Adonin, Nicolay Yu.;Fedin, Matvey V.. And the article was included in Nanoscale in 2020.Reference of 35487-17-3 This article mentions the following:

Intriguing nanostructuring anomalies have been recently observed in imidazolium ionic liquids (ILs) near their glass transition points, where local d. around a nanocaged solute progressively grows up with temperature Herewith, we for the first time demonstrate exptl. and theor., that these anomalies are governed by alkyl chains of cations and crucially depend on their length. ESR spectroscopy on a series of ILs [C_nmim]BF₄ (n = 0-12) shows that only the chains with n = 3-10 favor anomaly. Moreover, remarkable even vs. odd n peculiarities were systematically observed Finally, similar anomaly was for the first time observed for a non-IL glass of di-Bu phthalate, which structurally mimics cations of imidazolium ILs. Therefore, such anomalous d. behavior in a glassy state nanocage goes far beyond ILs and proves to be a more general phenomenon, which can be structurally tuned and rationally adjusted for various potential applications in nanoscale materials. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3Reference of 35487-17-3).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 35487-17-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Organic acid catalysed Minisci-type arylation of heterocycles with aryl acyl peroxides was written by Ouyang, Yani;Yue, Xiaoguang;Peng, Jiehai;Zhu, Jiashun;Shen, Qiuyuan;Li, Wanmei. And the article was included in Organic & Biomolecular Chemistry in 2022.COA of Formula: C8H8N2 This article mentions the following:

A metal-free method for the Minisci-type arylation of heterocycles with aryl acyl peroxides has been reported. This strategy enables the rapid and simple synthesis of a series of Minisci-type adducts from com. available starting materials without metal catalysts. A free-radical-pathway mechanism is suggested for this transformation. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3COA of Formula: C8H8N2).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.COA of Formula: C8H8N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Extraction of butan-1-ol from aqueous solution using ionic liquids: An effect of cation revealed by experiments and thermodynamic models was written by Domanska, Urszula;Wlazlo, Michal;Paduszynski, Kamil. And the article was included in Separation and Purification Technology in 2018.Safety of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide This article mentions the following:

Production of bio-butanol from biomass by fermentation in an aqueous phase needs new solutions and entrainers for the separation of product. Ionic liquids (ILs) are attractive significant attention as novel, low pressure solvents alternative to conventional organic solvents for biphasic solvent extraction Ternary liquid-liquid equilibrium data are presented for mixtures of {ionic liquid (1) + butan-1-ol (2) + water (3)} at T = 298.15 K and ambient pressure to analyze the performance of the IL in the extraction of butan-1-ol from aqueous phase. The bis{(trifluoromethyl)sulfonyl}amide-based ILs have been studied: octyltriethylammonium bis{(trifluoromethyl)sulfonyl}amide, [N_8,2,2,2][NTf₂], methyltrioctylammonium bis{(trifluoromethyl)sulfonyl}amide, [N_8,8,8,1][NTf₂], 1-dodecyl-3-methylimidazolium bis{(trifluoromethyl)sulfonyl}amide, [DoMIM][NTf₂] and 1-hexyloxymethyl-3-methylimidazolium bis{(trifluoromethyl)sulfonyl}amide, [C₆H₁₃OCH₂MIM][NTf₂]. The results are discussed in terms of the selectivity and the solute distribution ratio of separation for the related systems. The IL with three octyl alkyl chains, [N_8,8,8,1][NTf₂] at the ammonium-based cation shows higher selectivity and the same distribution ratio in comparison to the other ILs in this process. Addnl., the viscosity of [N_8,2,2,2][NTf₂], and d. and viscosity of the best IL, [N_8,8,8,1][NTf₂] were measured for the collection of physico-chem. properties of the ILs used in this work. The non-random two liquid NRTL model was used successfully to correlate the exptl. tie-lines. The prediction of ternary compositions was shown with good precision using COSMO RS for the ILs used in this work and for data from literature. The data and calculations presented here indicate the possible use of the model COSMO RS for the prediction of ternary LLE and of the use of [N_8,8,8,1][NTf₂], as a good solvent for the separation of butan-1-ol from water using solvent extraction In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Safety of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Safety of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of tin nanocrystals in room temperature ionic liquids was written by Le Vot, Steven;Dambournet, Damien;Groult, Henri;Ngo, Anh-tu;Petit, Christophe;Rizzi, Cecile;Salzemann, Caroline;Sirieix-Plenet, Juliette;Borkiewicz, Olaf J.;Raymundo-Pinero, Encarnacion;Gaillon, Laurent. And the article was included in Dalton Transactions in 2014.Quality Control of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide This article mentions the following:

The aim of this work was to study the synthesis of tin nanoparticles (NPs) or tin/carbon composites, in room temperature ionic liquids (RTILs), that could be used as structured anode materials for Li-ion batteries. An innovative route for the synthesis of Sn nanoparticles in such media is successfully developed. Compositions, structures, sizes and morphologies of NPs were characterized by high-energy x-ray diffraction (HEXRD), XPS and high-resolution TEM (HRTEM). (i) metallic tetragonal β-Sn was obtained and (ii) the particle size could be tailored by tuning the nature of the RTILs, leading to nano-sized spherical particles with a diameter ranging from 3 to 10 nm depending on synthesis conditions. To study carbon composite materials for Li-ion batteries, Sn nanoparticles were successfully deposited on the surface of multi-wall carbon nanotubes (MWCNT). Also, electrochem. properties were studied in relation to a structural study of the nanocomposites. The poor electrochem. performances as a neg. electrode in Li-ion batteries is due to a significant amount of RTIL trapped within the pores of the nanotubes as revealed by XPS studies. This dramatically affected the gravimetric capacity of the composites and limited the diffusion of lithium. The findings of this work however offer valuable insights into the exciting possibilities for synthesis of novel nano-sized particles and/or alloys (e.g. Sn-Cu, Sn-Co, Sn-Ni, etc.) and the importance of carbon morphol. in metal pulverization during the alloying/dealloying process as well as prevention of ionic liquid trapping. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Quality Control of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Quality Control of 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Lubrication Properties of the Ionic Liquid Dodecyl-3 Methylimidazolium bis(trifluoromethylsulfonyl)imide was written by Battez, A. Hernandez;Ramos, D.;Blanco, D.;Gonzalez, R.;Fernandez-Gonzalez, A.;Viesca, J. L.. And the article was included in Tribology Letters in 2018.Product Details of 404001-48-5 This article mentions the following:

The ionic liquid (IL) dodecyl-3 methylimidazolium bis(trifluoromethylsulfonyl)imide was tested as neat lubricant and as additive (at 1 and 4 wt%) in a polar oil (diester). Tribol. tests were performed using a reciprocating configuration for 90 min at 30 and 70 N, 10 Hz, 4 mm stroke length, and at room temperature and 100°C. Wear volume and surface-IL interaction were determined by confocal microscopy, SEM, and XPS. The main findings were: Neat ionic liquid showed the best tribol. behavior; the IL-containing mixtures had similar behavior than the base oil at the lower load; meanwhile, the mixture with 4 wt% of IL outperformed the antiwear behavior of the neat base oil at the higher load; surface-IL chem. interaction was found mainly at 100°C. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Product Details of 404001-48-5).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Product Details of 404001-48-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Properties and catalytic activity of magnetic and acidic ionic liquids: Experimental and molecular simulation was written by Zhou, Cunshan;Yu, Xiaojie;Ma, Haile;Huang, Xingyi;Zhang, Henan;Jin, Jian. And the article was included in Carbohydrate Polymers in 2014.Safety of 1-Methyl-3-propylimidazolium Chloride This article mentions the following:

The exploitation of dual functional magnetic and acidic ionic liquids (MAILs) for hydrolysis of cellulose to platform chems. can solve some practical challenges through easy separation of products and efficient catalyst recyclability. In this work, seven C_nmim/FeCl₄ MAILs were synthesized and investigated with combined exptl. and mol. dynamics. The MAILs contained FeCl^–₄ anions and exhibited a typical hard magnetic materials behavior with rather strong magnetic susceptibilities. These MAILs were stable up to 250-310 °C, the decomposition was started up at 250/310-480-810 °C in two steps with the formation of the undecomposed residue. The Gibbs energy for the reaction of glucose/xylose conversion to 5-hydroxymethylfurfural by metal chlorides in the C_nmimCl ionic liquid was studied using the d. functional theory calculations and the results that C₃mim/WCl₃ may be the most hopeful catalyst. The MAILs have the potential to open up promising new catalytic systems because of their easy product separation and efficient catalyst recyclability. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Safety of 1-Methyl-3-propylimidazolium Chloride).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Safety of 1-Methyl-3-propylimidazolium Chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Dynamic wetting of imidazolium-based ionic liquids on gold and glass was written by Delcheva, I.;Beattie, D. A.;Ralston, J.;Krasowska, M.. And the article was included in Physical Chemistry Chemical Physics in 2018.Synthetic Route of C18H31F6N3O4S2 This article mentions the following:

The present study explores the dynamic wetting of three ionic liquids (with a different length of hydrocarbon chain in the cation) on gold and glass substrates, both of which are relevant for nano- and micromech. machine applications, under well-controlled environmental conditions. The form of data capture (Wilhelmy plate) allows for a direct anal. using anal. expressions for the two dominant approaches for dynamic wetting: the hydrodynamic and mol. kinetic models. All ionic liquids yield data that are described best by the mol. kinetic model. Substrate-ionic liquid and water-ionic liquid interactions contribute to the mechanisms involved in the wetting process. In the experiment, the researchers used many compounds, for example, 3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5Synthetic Route of C18H31F6N3O4S2).

3-Dodecyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide (cas: 404001-48-5) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Synthetic Route of C18H31F6N3O4S2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis of 2-alkyl-substituted benzimidazoles by thermal decomposition of 2-azidobenzenamines in the presence of an aldehyde was written by Wallace, Jeffery M.;Soderberg, Bjorn C. G.;Hubbard, Jeremiah W.. And the article was included in Synthetic Communications in 2006.SDS of cas: 4887-83-6 This article mentions the following:

2-Substituted benzimidazoles, e.g., I, were prepared by reaction of 2-azidoaminobenzenes, e.g., II, with with aldehydes under thermal conditions. The reaction probably proceeds via a sequential imine formation, azide decomposition forming a nitrene, and electrocyclization. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6SDS of cas: 4887-83-6).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. SDS of cas: 4887-83-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem