Month: January 2023

Oxidized Charcoal-Supported Thiol-Protected Palladium Nanoparticles for Cross Dehydrogenative Coupling of Heteroarenes was written by Kumar, Sunil;Kumari, Sonu;Singh, Sohan;Boruah, Palash Jyoti;Paul, Amit Kumar;Roy, Partha;Joshi, Hemant. And the article was included in ACS Applied Nano Materials in 2022.Safety of 1-Methylbenzimidazole This article mentions the following:

This report described the synthesis of thiol-protected Pd nanoparticles (NPs) (Pd-MUA) (MUA = 11-mercaptoundecanoic acid) supported on oxidized charcoal (OC-Pd-MUA) at room temperature The Pd-MUA NPs and OC-Pd-MUA nanocomposites (NCs) were characterized with Fourier transform IR (FTIR) spectroscopy, transmission electron microscopy (TEM), energy-dispersive X-ray spectrometry (EDX), XPS and Brunauer-Emmett-Teller (BET) techniques. The size distribution curve revealed that the diameter of the nanoparticles was in the range of âˆ?-12 nm, and the surface area of the NCs was found to be 138.449 m²/g. The as-prepared OC-Pd-MUA NCs were used as a catalyst for the cross dehydrogenative coupling (CDC) of two different heteroarenes. Remarkably, the catalyst was found to be very efficient in activating various heteroarenes under mild reaction conditions. Most importantly, no homocoupled or other byproducts were observed during the heterocoupling reactions. Moreover, the catalyst can be potentially used for the homocoupling reaction of various heteroarenes. It is noteworthy that only 0.22 mol % catalyst loading was required to activate a broad substrate scope with large functional group tolerance. Notwithstanding, the efficacy of the catalyst was found to be retained even after six reaction cycles. The reusability and hot filtration tests validated the heterogeneous nature of the catalysis. In addition, the exptl. and computational studies collectively suggested that thiophene derivatives react to produce energetically stable products compared with other heteroarenes during the reaction. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Safety of 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Safety of 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Correlation of molecular structure and polarity of ionic liquids was written by Spange, Stefan;Lungwitz, Ralf;Schade, Alexander. And the article was included in Journal of Molecular Liquids in 2014.SDS of cas: 35487-17-3 This article mentions the following:

The empirical Kamlet-Taft solvent parameters for hydrogen bond donating (HBD) ability (α), hydrogen bond accepting (HBA) ability (β), and dipolarity/polarizability (π*) have been determined for 102 ionic liquids (ILs). α, β, and π* have been measured by means of the solvatochromic methods utilizing three specific dyes Fe(phen)₂(CN)₂ (Fe), 3-(4-amino-3-methyl-phenyl)-7-phenyl-benzo-[1,2-b:4,5-b’]-difuran-2,6-dione (ABF) and 4-tert-butyl-2-(dicyanomethylene)-5-[4-(diethylamino)benzylidene]-Δ³-thiazoline (Th) each solely sensitive to one of the Kamlet-Taft parameter. Different types of ILs with various cation structure such as 1,3-dialkyl imidazolium and 2- and 4-,5-Me substituted derivatives, pyridinium, tetraalkylammonium, trialkylsulfonium and tetraalkylphosphonium were used. In conjunction to the [C₄mim] cation, more than 20 various established anions, such as halides, tetrafluoroborate, dicyanamide, were considered in this study. The frontiers of HBA ability strength of the anions are marked by the specific anions azide (N₃^–) (large β) and FAP PF₃(C₂F₅)₃^– (lowest β). The linear intercorrelation between α and β is clearly evidenced, which shows that anion and cation interact with each other, for each type of IL used. Also correlation of mol. structure of the cation and the HBD ability can be recognized and supported by results from NMR spectroscopy. The interpretation of π* is still not satisfied because dipolarity and polarizability of each IL obviously contribute in different proportions to the value. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3SDS of cas: 35487-17-3).

1-Methyl-1H-imidazol-3-ium chloride (cas: 35487-17-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.SDS of cas: 35487-17-3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ionic liquid surfactants as multitasking micellar catalysts for epoxidations in water was written by Schmidt, Fabian;Zehner, Bastian;Korth, Wolfgang;Jess, Andreas;Cokoja, Mirza. And the article was included in Catalysis Science & Technology in 2020.Product Details of 21252-69-7 This article mentions the following:

We present a single-component catalyst system for the epoxidation of hydrophobic olefins in aqueous solution The aggregation of surface-active 1-alkyl-3-methylimidazolium ionic liquids (IL) containing the catalytically active tungstate dianion leads to micelles, which solubilise apolar olefins in aqueous media. The micellization of tungstate allows for the epoxidation of cyclooctene and other olefins in water, using environmentally benign hydrogen peroxide as oxidant. The structural characterization of the micelles under catalysis conditions as well as the substrate uptake have been studied by cryo-TEM. ¹⁸³W-NMR studies revealed that the catalytically active species is a tetraperoxotungstate complex. The addition of organophosphonic acids results in a significant boost of the catalytic activity by formation of a tungstate-phosphonate adduct, investigated using electrospray ionization mass spectrometry (ESI-MS). The versatile functionalisability of the imidazolium cation enables a covalent linkage of a phosphonate group, which is further increasing the catalytic activity. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Product Details of 21252-69-7).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Product Details of 21252-69-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Metalloporphyrin and Ionic Liquid-Functionalized Covalent Organic Frameworks for Catalytic CO₂ Cycloaddition via Visible-Light-Induced Photothermal Conversion was written by Ding, Luo-Gang;Yao, Bing-Jian;Wu, Wen-Xiu;Yu, Zhi-Gao;Wang, Xiao-Yu;Kan, Jing-Lan;Dong, Yu-Bin. And the article was included in Inorganic Chemistry in 2021.Application In Synthesis of 1-Methylbenzimidazole This article mentions the following:

We report the construction of a porphyrin and imidazolium-ionic liquid (IL)-decorated and quinoline-linked covalent organic framework (COF, abbreviated as COF-P1-1) via a three-component one-pot Povarov reaction. After post-synthetic metalization of COF-P1-1 with Co(II) ions, the metalized COF-PI-2 is generated. COF-PI-2 is chem. stable and displays highly selective CO₂ adsorption and good visible-light-induced photothermal conversion ability (ΔT = 26°). Furthermore, the coexistence of Co(II)-porphyrin and imidazolium-IL within COF-PI-2 has guaranteed its highly efficient activity for CO₂ cycloaddition Of note, the needed thermal energy for the reactions is derived from the photothermal conversion of the Co(II)-porphyrin COF upon visible-light irradiation More importantly, the CO₂ cycloaddition herein is a “window ledge” reaction, and it can proceed smoothly upon natural sunlight irradiation In addition, a scaled-up CO₂ cycloaddition can be readily achieved using a COF-PI-2@chitosan aerogel-based fixed-bed model reactor. Our research provides a new avenue for COF-based greenhouse gas disposal in an eco-friendly and energy- and source-saving way. In the experiment, the researchers used many compounds, for example, 1-Methylbenzimidazole (cas: 1632-83-3Application In Synthesis of 1-Methylbenzimidazole).

1-Methylbenzimidazole (cas: 1632-83-3) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Application In Synthesis of 1-Methylbenzimidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem